LAIR1 has been associated with the pathogenesis of several autoimmune diseases, including systemic lupus erythematosus (SLE) [174], rheumatoid arthritis (RA) [175], allergy (airway hyper-reactivity and asthma) [176], graft rejection (kidney transplant) [177], and chronic hepatitis [178]. Here, LAIR1 is linked to systemic lupus erythematosus.