According to Lu et al. [32], in the FaDu/Twist+ hypopharyngeal carcinoma cell line, caspase-3, caspase-9, Bcl-2, and Bax exhibited alterations favoring anti-apoptosis, suggesting that Twist1 expression may promote chemotherapy resistance by suppressing apoptosis. This evidence concerns the gene TWIST1 and hypopharyngeal carcinoma.