Immunofluorescence staining showed that the proportion of IBA1+CD86+ (M1-like) microglia was reduced and that of IBA1+CD206+ (M2-like) microglia was increased in both the miR-21-5p agomir + AIH and S3I-201 + AIH groups compared with the AIH and NC groups (Figure 5D–G). Here, CD86 is linked to autoimmune hepatitis.