Moreover, the prognostic value of the Ki-67 index was improved using alternative Ki-67 index thresholds suggested by Scarpa et al. (G1: Ki-67 ≤5%, G2: Ki-67 >5% and ≤20%, G3: Ki-67 >20%) which yielded higher hazard ratios compared to the European Neuroendocrine Tumor Society (ENETS) Ki-67 index thresholds [4,10]. The gene discussed is MKI67; the disease is neoplasm.