A survival analysis was performed using univariate Cox proportional hazards regression as well as plotting Kaplan–Meier survival curves, and the results, as shown in Table S25 as well as Figures S11 and S12, revealed that six genes, FEN1, FADS1, FADS3, RAB3IL1, NRBP1 and ZNF512, were significantly associated with overall survival in CRC patients (pfdr < 0.05). The gene discussed is FADS3; the disease is colorectal carcinoma.