CCT3 and colonic neoplasm: After the stratification of colorectal adenocarcinoma patients according to their tumor location, we noticed that patients with colon tumors (122 for DFS and 136 for OS) and the overexpression of circ-CCT3 showed significantly shorter DFS intervals (p = 0.032) and OS intervals (p = 0.005) (Figure 5A,B).