Finally, public RNA-seq data from 93 leukemia cell lines for the identified NKX6-3 target genes show reduced activity of CD109 and overexpression of GP5 and MPP7 in RCH-ACV and MHH-CALL-3 (Figure S7), highlighting the suitability of these cell lines as models for their investigation in follow-up studies. The gene discussed is NKX6-3; the disease is leukemia.