CLIP4 and systemic lupus erythematosus: Τhe in silico analysis shows that rs10166913 is associated with enhancer modifications (H3K4me1, H3K27ac) in skin cells, which could potentially affect expression of the nearby ubiquitously expressed gene CLIP4 (~25 Kb downstream), previously identified as self-antigen in systemic lupus erythematosus (SLE) associated with disease onset and activity [61].