COL2A1 and Stickler syndrome: A recent meta-analysis of 400 eyes of 225 patients with COL2A1- or COL11A1-related Stickler syndrome reported an RD rate of 6.6% (6.3 years mean follow-up duration) in patients who had prophylactic laser retinopexy compared to 36.0% (4.0 years mean follow-up duration) in patients without laser [36].