In our analysis of associations between clinical parameters and genetic groups linked to T2D, including appetite/energy regulation, β-cell function/insulin secretion, glucocorticoid signaling, insulin signaling/metabolism, mitochondrial function, neurotransmission, non-coding RNA/epigenetics, and vasopressin signaling, we observed pronounced differences for two key traits (Supplementary Figure S1). The gene discussed is INS; the disease is type 2 diabetes mellitus.