IGHE and wheat allergic reaction: Using various wheat extracts and purified ω-5 gliadin (native and recombinant) as stimuli, the BAT achieved a sensitivity of ~85% and specificity of ~77% for native ω5G (corresponding to area under the ROC curve ~0.89, as shown in Table 2), outperforming the conventional wheat-specific IgE test and indicating that the BAT with nω5G is especially sensitive for wheat allergy.