The analysis data showed that patients also carried variants in genes associated with AVSD (e.g., COL11A1, DNAH11, GATA4, LRP2, MYH6, NFATC1, NKX2-6, NOTCH1, SRCAP, TBX1, and ZFPM2), TGA (e.g., COL11A1, GDF1, LRP2, MYH6, and TBX1), or hypoplastic left heart (e.g., LRP2, MYBPC3, MYH6, and NOTCH1). This evidence concerns the gene MYBPC3 and familial atrioventricular septal defect.