Additionally, in both splenectomized and non-splenectomized groups, pulmonary disease and non-pulmonary disease groups, groups with and without monoclonal gammopathy, and groups with and without liver disease, the gpNMB value was effective in distinguishing Gaucher patients from healthy controls (p < 0.05) (Fig. 3). The gene discussed is GPNMB; the disease is liver disorder.