The TCGA-TNBC cohort tumours revealed a correlation between the ST6GALNAC1 and macrophages M2 and Tregs, which exert pro-tumorigenic effects through the release of cytokines and chemokines, such as IL-10 and TGF-β, that support tumour growth and promote an immune suppressive environment and consequent immune evasion58,59. This evidence concerns the gene IL10 and neoplasm.