Previous studies have confirmed that YAP1 may partially reverse the inhibitory effect of SNTB1 knockdown on the phenotype of CRC cells and the Wnt/β‐catenin/MYC signaling pathway, thereby affecting the invasiveness of colon cancer cells and the growth and metastasis of tumors in vivo [38]. This evidence concerns the gene SNTB1 and malignant colon neoplasm.