IGF1 and post-traumatic stress disorder: In Past PTSD ≤ 5 y, low IGF-1 (0–10 nmol/mL) indicates a suppressed neuroprotective state, likely driven by HPA axis dysregulation, correlating with impaired adaptive coping (e.g., Problem-Focused: 10–16/32) and elevated avoidance (21–29/32).