In Past PTSD > 5 y, the negative correlation between IL-10 and Problem-Focused Coping (Rho = −0.29; Figure 6A) demonstrates that despite increasing IL-10 levels (291.25–2157 ng/L), active coping remains impaired, possibly reflecting learned helplessness or persistent negative alterations in cognition (Criterion D). This evidence concerns the gene IL10 and post-traumatic stress disorder.