ADCY4 and ductal breast carcinoma in situ: Three microarray profiles containing expression data on DCIS and IDC lesions were downloaded (GSE35019, GSE33692, and GSE14548; Supplemental Tables S1 and S2) and merged (Figure 2a), which led to the identification of 13 DEGs (C7, MMP13, PAMP3, KCNK5, GABRB2, PLAU, SELP, COL11A1, KIAA1199, MT1M, ADCY4, COL5A2, and MMP11) (Figure 2b,c; Supplemental Table S3).