TNF and Hepatic steatosis: Hepatic steatosis perturbs mitochondrial homeostasis and activates nuclear factor kappa B (NF-κB), thereby amplifying inflammatory cascades and inducing the release of cytokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) [16].