According to Xiangyi Ma et al. 2024 [1], the upregulation of histone modifications at chr12p13.32—including methylation (H3K4me, H3K4me3) and acetylation (H3K9ac, H3K27ac)—activates the expression of lincRNA GAU1 and the oncogene GALNT8, both of which contribute to retinoblastoma progression [67]. The gene discussed is GAU1; the disease is retinoblastoma.