EGFR and colorectal carcinoma: A molecular docking study revealed molecular interactions between coclaurine, reticuline, and CRC receptors (i.e., TRAF2 and Nick interacting kinase (TNIK), vascular endothelial growth factor receptor (VEGFR), epidermal growth factor receptor (EGFR)), suggesting that both alkaloids could be potential anti-CRC drugs [21].