Additionally, we performed a Spearman’s correlation test to observe the correlation of PRMT5 gene expression with 10 classical hypoxia gene markers (P4HA1, ENO2, NEDD4L, HK2, LDHA, FOXO3, SLC2A1, BHLHE40, PGGK1, BNIP3L) using TCGA breast cancer tumor gene sets (BRCA Tumor). This evidence concerns the gene ENO2 and neoplasm.