CCL11 was downregulated in media with a high concentration of n-3 LCPUFA and no vitamin D, whereas it was upregulated in media with a high concentration of n-3 LCPUFA and low vitamin D. Elevated levels of CCL11 were commonly observed in patients with asthma, allergic rhinitis, and atopic dermatitis [50]. The gene discussed is CCL11; the disease is atopic eczema.