Notably, TMEM207-positive tumors exhibited a significantly lower incidence of lymph-node metastasis (2/38, 5.3%) compared to TMEM207-negative counterparts (54/178, 30.3%; p < 0.001), suggesting a potential role for TMEM207 in limiting metastatic dissemination. This evidence concerns the gene TMEM207 and metastatic malignant neoplasm in the lymph nodes.