PROM1 and hepatocellular carcinoma: Literature further supports functional roles for individual markers: CD24 overexpression correlates with chemoresistance and poor prognosis [109,110]; CD44 promotes HCC progression via YAP signaling [111]; CD133 identifies chemoresistant subpopulations [112,113,114,115,116]; and ALDH1 is linked to tumorigenicity and adverse prognosis [117,118,119,120,121,122,123,124,125].