Similarly, while Flores Legarreta et al. reported frequent multigene alterations and immune-biomarker positivity in ovarian neuroendocrine neoplasms, the combined presence of BRCA2 frameshift, ATM nonsense, MSI-H, and ultra-high TMB exceeding 200 mutations/Mb has not been documented to date. Here, BRCA2 is linked to ovarian neuroendocrine neoplasm.