PASP, according to ROC analysis, predicts severe/very severe stages of COPD with an AUC of 0.804 (95% CI: 0.691–0.918, p = 0.001 < 0.05), an optimal cutoff value of 37.50 mmHg, with a Sp of 46.9% and a Se of 87%. This evidence concerns the gene CPB1 and chronic obstructive pulmonary disease.