The cell lines represent different molecular breast cancer subtypes, including the luminal A (MCF-7), luminal B (BT474), HER2-positive (SKBR3, MDA-MB 453), triple-negative A (basal-like) (MDA-MB 468, HCC1806, BT20), and triple-negative B (normal-like/claudin-low) (MDA-MB-231, BT549, SUM149 subtype [26]. Here, ERBB2 is linked to breast cancer.