Notably, NSUN2—the most extensively studied paralog—has been associated with the progression of hepatocellular carcinoma, pancreatic cancer, breast cancer, and other malignancies [121,122,123], NSUN5 has likewise been linked to hepatocellular carcinoma and gastric cancer [124,125], and NSUN6 has been reported in connection with cervical cancer and glioma [126,127]. Here, NSUN5 is linked to hepatocellular carcinoma.