These metaclusters elevated in HIV-positive pre-NHL had the following phenotypes: CD14+HLA-DR+CD11b+CD4−CXCR4− (MC08), CD14+HLA-DR+CD11b+CD4+BCL-6−CXCR4+ (MC07), and CD14+HLA-DR+CD11b+CD4+CXCR4+ (MC05) monocytes. This evidence concerns the gene CD14 and non-Hodgkin lymphoma.