CFTR and cystic fibrosis: To evaluate whether individual treatment with the corrector VX-809 (which theoretically increases CFTR levels at the plasma membrane) or the potentiator VX-770 (which enhances the channel’s open probability) [82] could reduce ROS production, we measured cROS and mtROS in CF cells using DCFH-DA and MitoSOX fluorescent probes, respectively.