In contrast, CD200R expression on CD4+ and CD8+ T cells was significantly increased in CLL+SID patients compared to both CVID and HV (p < 0.001; Figure 1A,B), while no significant differences were found between CVID and HV for CD4+ cells (Supplementary Materials Table S1). The gene discussed is CD4; the disease is B-cell chronic lymphocytic leukemia.