CRP and Increased total leukocyte count: Mirijello et al. [181] described a patient with amoxicillin-clavulanate–induced anaphylaxis whose elevated PCT levels, leukocytosis, and chest radiographic abnormalities initially suggested septic shock, while Kim et al. [182] reported risedronate-induced anaphylaxis in a 74-year-old woman with marked CRP and PCT elevations, again masquerading as sepsis until drug rechallenge clarified the diagnosis.