The adipo-IR index was approximately 40% lower in iAd-Fam20c–KO mice compared with controls (0.75 ± 0.04 vs. 1.24 ± 0.46, P = 0.03), suggesting that Fam20c deletion ameliorates AT insulin resistance (Figure 3L). This evidence concerns the gene FAM20C and ataxia telangiectasia.