The persistent fibrosis observed in OGC+/− mice aligns with previous reports of significantly lower GSH levels in idiopathic pulmonary fibrosis (Beeh et al. 2002), and liver fibrosis (Fraser et al. 2022; Huang et al. 2023), suggesting a potential role for GSH in this process. The gene discussed is SLC25A11; the disease is Hepatic fibrosis.