ADIPOR1 and type 1 diabetes mellitus: In both type 2 (Fig. 5c) and type 1 diabetes (Fig. 5d) models, knockdown of AdipoR1 nearly abrogated the pro-repair effect of ADPN on corneal epithelial injury, whereas AdipoR2 silencing had no such impact, indicating that ADPN promotes corneal epithelial repair specifically through AdipoR1.