Exendin-4 and liraglutide also promote neurogenesis in the dentate gyrus of PreDM and T2D mice [71], exenatide increases Ngf expression in the hippocampus of T2D mice [72], and liraglutide and Val8GLP1 restore hippocampal LTP, disrupted by HFD [73, 74]. Here, NGF is linked to type 2 diabetes mellitus.