This includes for example for bendamustine ARID5B associated with susceptibility of childhood acute lymphoblastic leukemia and treatment outcome  [61], CD38 associated with cell survival and proliferation in chronic lymphocytic leukemia  [62], and the oncogene MYB involved in different leukemias  [63] (Fig. 4). The gene discussed is CD38; the disease is B-cell chronic lymphocytic leukemia.