These “myelodysplasia-related gene mutations” (MR gene mutation, also called secondary-type mutations) include mutations in the genes SRSF2, SF3B1, U2AF1, ZRSR2, ASXL1, EZH2, BCOR, and STAG2. The ICC 2022 [2] definition of MR gene mutations includes RUNX1 mutations as an MR gene mutation while the WHO 2022 [3] only includes the aforementioned eight mutations. The gene discussed is NR3C2; the disease is Myelodysplasia.