Of the 22 hepatic NEN, 14 (63.6%) exhibited Ki67-positive staining of more than 20% of tumor cells, 5 (22.7%) cases had between 3 and 20% Ki67-positive tumor cells and the remaining 3 (13.6%) cases had less than 3% Ki67-positive tumor cells (Table 1). This evidence concerns the gene MKI67 and neoplasm.