BCL6 and malignant colon neoplasm: However, when BCL6 levels in CD8 T cells were analyzed across scRNA-seq datasets from colon cancer samples, we found cytotoxic or effector CD8 T cells had higher expression of BCL6 (Figs 1A and S1H), which is encouraging for studying the distinct gene suppressive function of BCL6 in T-cell responses during cancer.