Moreover, tumor-infiltrating CD8 T-cell levels and Bcl6 expression showed a positive correlation in COAD, PAAD, and READ samples (Fig S1E–G), suggesting that tumor-intrinsic BCL6 expression is associated with a more aggressive malignant phenotype, even in the presence of increased T-cell infiltration. This evidence concerns the gene BCL6 and pancreatic adenocarcinoma.