The intricate role of genetics in the etiology of ET is underscored by the high prevalence of positive family history in patients, ranging from 20 to 90%, and the phenomenon of genetic anticipation, where tremor manifests at an earlier age in successive generations.43, 44Genome-wide association studies (GWAS) have identified several genetic variants in genes such asLINGO1,SLC1A2,STK32B,PPARGC1A, andCTNNA3linked to ET, though these findings have yet to be replicated consistently. Here, SLC1A2 is linked to essential thrombocythemia.