The high frequency of TP53 mutations (in 3/4 BC and 2/2 HGSC samples) is in agreement with previous studies [10, 28], while other common drivers, such as EGFR, PTEN, CDH1, CDKN2A, APC, ATM, and MAP2K1, were found to be mutated in our study. This evidence concerns the gene APC and breast cancer.