ARL5B and neoplasm: ARL5B expression exhibited a stepwise elevation across tumor stages (H‐score analysis, normal tissue vs stage I, p < 0.05; stage I vs stage II, p < 0.01; stage I vs stage III, p < 0.001; stage I vs stage IV, p < 0.001), with stage IV lesions showing the most intense staining (Figure 1C, right).