Activated AKT then triggers mTOR, a serine/threonine protein kinase existing in two distinct complexes: mTOR Complex 1 (mTORC1) and mTOR Complex 2 (mTORC2).[103, 104, 105, 106] AKT activates mTORC1 by inhibiting the tumor suppressor TSC1/2, promoting key anabolic processes essential for cancer cell proliferation.[107]. Here, AKT1 is linked to cancer.