This approach increases local drug concentrations within tumors while simultaneously reducing systemic toxicity to healthy organs.[45, 46, 47] On the other hand, the intrinsic catalytic activities of nanozymes, such as their peroxidase (POD)‐like, catalase (CAT)‐like, and superoxide dismutase (SOD)‐like functions, can be strategically harnessed to intricately modulate the tumor microenvironment (TME). This evidence concerns the gene CAT and neoplasm.