This could be attributed to the protective role of MSCs-Exo+EVOO against hepatic steatosis via promoting lipid oxidation related factors, PPARα, CPT-1, and ACOX, involved in fatty acid oxidation and suppressing synthesis of fatty acid via controlling PPARα, CPT-1A, SREBP-1, and FAS expression. Here, ACOX1 is linked to Hepatic steatosis.