The results revealed significantly increased mRNA levels of METTL7A, SERPINB6, VASP, and ENTPD2, whereas FIBP, FUCA1, TARBP1, SORCS3, and DMXL2 exhibited reduced mRNA expression in the AD-associated tau and Aβ pathology model (Figures 12, 13). The gene discussed is SORCS3; the disease is Alzheimer disease.