The diagnosis of KS was based on clinical presentation; a history of previous allergies; laboratory tests, such as troponin I, eosinophil count, serum trypsin, histamine metabolite (N-methylhistamine) in 24-h urine, and prostaglandin D2 (PGD2, 11-β-PGF2α) and the levels of cardiac enzymes (CK, CK-MB), C-reactive protein, immunoglobulin E and interleukin-6; and findings from ECG, such as ST elevation myocardial infarction; and coronary angiography, such as coronary vasospasm, echocardiography and magnetic resonance imaging (3, 8, 15). The gene discussed is IL6; the disease is coronary vasospasm.