IL2RA and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: Figure 1D shows an abnormality in the immune evaluation. Among the 15 patients, six had low Treg cells in the peripheral blood, including four of eight with LRBA deficiency, one of one with IPEX, and one of one with CD25 deficiency (Figure 1E). Detailed immunophenotypes and descriptions of autoantibodies for each patient are included in Table 1; Supplementary Table S1, and Supplementary Figure S1.