EBV+FL is most frequently classified as grade 3A or 3B.The tumor cells express B-cell-associated antigens (such as CD19, CD20, and CD79a),and are positive for BCL2, BCL6, and MUM1.CD10 is generally positive; however, it may be negative in some cases, particularly in grade 3B follicular lymphoma (10).Furthermore, compared to EBV-negative follicular lymphoma, CD30 expression is more frequently detected in EBV+FL (8).In this case, CD30 positivity was observed in approximately 1% of cells, while PD-L1 positivity reached 80%. This evidence concerns the gene MME and neoplasm.