Despite the fact that the survival data from our Pakistani cohort were not accessible, supportive Kaplan–Meier survival analysis employing TCGA pancreatic cancer dataset revealed that concurrent overexpression of MUC3A, MUC4, MUC13, and MUC16 was significantly associated with poor DFS, with a hazard ratio (HR) of 1.8 and a log‐rank p value of 0.0097. This evidence concerns the gene MUC16 and familial pancreatic carcinoma.